To the example of Stanford, they wrote an excellent book on finding and solving problems in the medical device context that is largely the bible for creating new medical devices.
The book grew out of an interdisciplinary institute between their MBA, engineering school, and med school programs that's considered the gold standard.
http://biodesign.stanford.edu/
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University of Michigan and Columbia are two of the other big players who play the medical device patent game well.
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My experience is in medical devices, but there are plenty of examples where faculty may have subject matter expertise in things like specific areas of signal processing or metalurgy. Those labs tend to spin off additional startups and labs operated by post-docs and alumni of the initial research leader's work. For example, there is a guy at University of Louisville who has worked on something like 14 commercialized surgical tools in his specific surgical niche.