I left my 4 boys alone for 3 nights recently. Aside from hiring a stranger, I have no one to look out for them while I'm gone. They're not super tame yet and are quite a handful, so I trusted in leaving them alone the most. I cleaned the cage right before leaving, left them a mountain of food in a big bowl, put in new toys, hammocks and hideouts, hid treats in the cage, hid well packaged packets of food in hard to reach places, threw in a couple of walnuts and hazelnuts in shell, gave them a deer antler to chew on. I also left them with 5 water bottles (including one for parrots) in case one of them leaks or malfunctions. Also, I have a huge cage (good for 17 rats according to rat cage calculator), so they had plenty of space for play and exercise. They are all young and very healthy, get along great, so I wasn't too worried. They were all more than fine when I returned.
Your rats will be fine too, though I would recommend an additional super reliable water bottle/water dispenser. I got my boys this cool fountain for next time I have to leave them alone.