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These things gave me my ability to game back. I had a full wrist lock up where I had to physically pull my wrist out of a locked state.
These gloves make your hands happy.
For a while I had some wrist pains in my mousing hand. Getting a wrist wrap/glove helped a huge amount! Haven't had any real pains since I started using it -
Pretty cheap/easy to try out at least, and if that doesn't help can always move onto other solutions.
IMAK have some good gloves, eg. [link]
what about this? it has a thing to support your wrist.