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I use one of these: http://www.amazon.com/gp/product/B00FZM93C4?keywords=lap%20desk%20pillow&qid=1444571262&ref_=sr_1_4&sr=8-4
with one of these on top: http://www.amazon.com/Uncaged-Ergonomics-Swivel-Rotating-Tabletop/dp/B00FIOLMWS/ref=sr_1_39?ie=UTF8&qid=1444571366&sr=8-39&keywords=laptop+stand
with the laptop on top of both, of course.
I did use a piece of thick plastic to fill in that "hole" on the right side of the lap desk which I then covered over with a cloth mouse pad cut to fit over that area. Using a high resolution mouse (Logitech gamer mouse -- G502) it works great.
Know that my laptop is a 15.6 widescreen Sager NP8265, so it's a little larger than most laptops of the same approximate size.
TL;DR - You'll not ever find the perfect solution in one item, but if you mix and match to fit your needs, you can make something that will work great!
Disclaimer: I'm a Linux user who uses Windows for games only, not that this has anything to do with anything but it amuses me to say.