Yes. Rigor Mortis: How Sloppy Science Creates Worthless Cures, Crushes Hope, and Wastes Billions by Richard Harris, an NPR reporter.
> An essential book to understanding whether the new miracle cure is good science or simply too good to be true > > American taxpayers spend $30 billion annually funding biomedical research, but over half of these studies can't be replicated due to poor experimental design, improper methods, and sloppy statistics. Bad science doesn't just hold back medical progress, it can sign the equivalent of a death sentence for terminal patients. In Rigor Mortis, Richard Harris explores these urgent issues with vivid anecdotes, personal stories, and interviews with the top biomedical researchers. We need to fix our dysfunctional biomedical system -- before it's too late.
https://www.amazon.com/Rigor-Mortis-Science-Worthless-Billions/dp/0465097901
Rigor Mortis: How Sloppy Science Creates Worthless Cures, Crushes Hope, and Wastes Billions American taxpayers spend $30 billion annually funding biomedical research, but over half of these studies can't be replicated due to poor experimental design, improper methods, and sloppy statistics. Bad science doesn't just hold back medical progress, it can sign the equivalent of a death sentence for terminal patients.
Failure to reproduce a finding could be for a plethora of reasons, so it's not that simple (and believe me, I wish it was!). If one group cannot reproduce a finding, it doesn't mean that the finding is immediately false and needs to be redacted. There are often technical reasons and experimental details that account for the difference, but it takes some effort from both parties to parse these out. Further, it's still incredibly difficult to get people motivated to take the time to write a manuscript and publish negative data, when they just want to move onto a new project instead.
As far as we're aware, lying and straight up malice are very small contributors to the reproducibility issue. I recommend reading Rigor Mortis to expand on much of this.
NC doesn't say that science is mishandled. I think you're misreading. But I'm not being very clear, so I take blame.
Are you interested in shitty science? There's a great book on it called Rigor Mortis (funny pun, get it?): https://www.amazon.com/Rigor-Mortis-Science-Worthless-Billions/dp/0465097901.
It deals with biomedical shit, but obviously there's shitty science all over the place.
There's a replication-crisis in psychology right now, for example: https://www.theatlantic.com/science/archive/2018/11/psychologys-replication-crisis-real/576223/.