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Spyderco Native 5 FRN Handle. The blade steel is excellent, the ergonomics are second to none, it's small and light and fits comfortably in my pocket. Plus the short blade keeps it from being too intimidating when I take it out to use.
Spyderco Native. Best blade steel and ergonomics for the price.
Spyderco is an excellent choice for a working knife. I would suggest that you go for a level above the Efficient and Tenacious to get a better quality steel. They aren't bad, but better will hold an edge longer. I also prefer other locks types to the liner lock.
If you really like the McBee do some shopping around. It is available for around $130.
My first choice would be the Spyderco Native 5. The design has been around a long time because everything about it works. The current versions come with S30V steel, which is excellent.
My second choice would be the Manix 2. It has one of the most secure and ergonomic grips you can on a knife.
You should also consider the Delica 4. It is the classic Spyderco design and meets all of your (and my) requirements. Unlike the others, you can get it in a half-serrated version.
In that range, I love the
Spyderco C41PBK5 Native5 Lightweight Black Plain Edge FRN Handle Knife
Any decent knife these days is going to have a detent to keep the blade from deploying prematurely.
In addition to lock-backs (the best of which is the Native) there is Benchmades Axis lock. It doesn't use a detent, but uses spring pressure to jam the lock pin into a milled flat on the back of the blade. Something like a Mini-Grip carries very securely.