Well my feeling is that as we get higher and higher in resolution in monitors an sensors and such, the little things will stand out more and more. If you haven't already, take a look at Stephen Shore's Uncommon Places book some time (or just go to a barnes and noble and peek) and be prepared to be wowed at how sharp and detailed the photos he took in the 70's are. Of course, he used large format, but it was inspiring to me.