Read the book called "cold email manifesto" by Alex Berman, you will get to know everything you need to know about sending cold emails. I scrape email leads from Instagram using Instascrape.info , go through the list, carefully chose the list, and send personalized emails to just 1 person.
Target just 1 person, and ask them something like "Should I talk to you about X or your CEO", this triggers the ego of the person to respond if they're actually in charge of taking action if not they will probably guide you to the person who you should email.
You can retarget them but do it by replying to the previous email that you sent and reminding them about the previous email, if they still didn't reply, send a 3rd email saying you won't email them further and consider them uninterested in your product. The last is important, it says to the client you're not another spammer and they're genuinely missing out on an opportunity.