If you're lucky enough to have a doctor working with you, I highly recommend this book: http://www.amazon.com/Tired-Thyroid-Hyper-Healing-Breaking/dp/1495355535/ There are numerous medical journal references so you can figure out what the truth is, and what's BS. If you can get your doctor to read it, even better. I cannot take 100% desiccated, but find it works well for me combined with T4. That gets me very close to the physiological levels I mentioned earlier.
The only argument I can think of against desiccated is that it is a higher T3/T4 content than humans. But that's exactly what YOU need right now!