The game might run (as noted, check appdb at winehq), but the installer is another question altogether. Most likely it has difficulties accessing the drive.
Did you mount the .iso natively within a file browser? Give ActetoneISO a try, and if this returns errors, try to mount the iso with an wine-started optical-drive emulator like "WinCDEmu" or "daemontools-lite". As they introduce their own drivers to mimick the device it will be interesting if it works.
also, check out cdemu
and report back :)