that kind of size, I'd recommend avoiding most of the major players such as Opera or Brilliant. You won't get value for your money.
Instead, I'd look for some of the newer startups. I have zero experience with these, so do your due diligence, but these look like decent candidates:
https://www.innroad.com/solutions/
http://www.frontdeskanywhere.com/
I would contact all of these and ask for them to set up a demo either by Webex or in person.
Thank you for your reply this is my first reddit post , all what you said here an example of hotel mangment written in php :- http://www.hotelogix.com/hotelogix-frontdesk-management-system.php
Also here a link of list of hotel mangment :- http://www.softwareadvice.com/hotel-management/
Is there any software like the above in python ?
What also the best framework in python for this type of software( pyramid , tornado ...).