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This, CLZ Comics? [link]
There's a few other ones. I edited my post, that might change your answer.
You'll want to get the CLZ Comics app for either iOS or Android. I believe they've got a desktop app and other options on their website, as well.
Yes and no. There is software, such as CLZ Comics for Android and iOS that will scan barcodes and allow you to organize the collection, but it doesn't include guide value. At the very least it should give you something much easier to look through than a few dozen boxes of comics though.
There's also equivalent desktop software but it's pricier and will require some kind of barcode scanner hardware (or smartphone software).