I run a dual setup in my 40 gallon long tank; a canister alongside a HOB. I love this setup and recommend it to anyone for larger tanks. It gives you the large size of the canister filter for a good amount of bio media, but you also have the HOB to add any small little things you need to for the tank. For example, in my HOB, I run filter floss, foam, and purigen. While in my canister I run bio balls, foam, and PhosGuard. Oh and I should mention that the HOB I use is an AquaClear 50, and the canister is an Eheim Classic 2215. Specs on those: Eheim: 164 GPH Total Filter volume of 1.1 Gallons Rated for tanks up to 92 US Gallons AquaClear 200 GPH max (depends on how much filter media is inside) Rated for tanks up to 50 gallons