Well you could run Scribus under VNC (like you could any software, e.g. Inkscape, Libre Office) and then people could go into the VNC session and run it, they would sharing the single instance and would have to be mindful not to step on each other's activity. Or, if you have a limited number of people, say 20, each could have a VNC session (:1 - :20) where they'd run their own Scribus session. But I'm probably going beyond what you originally wanted with this suggestion.
scribus does work on mac 64 bit and both InDesign and Scribus are layout programs that produce PDFs.
They have a slightly different features set and InDesign is often seen as more polished. You can freely download and test Scribus to see if it fits your needs:
Personally, I'd do the booklet by orienting the page with one half rightside-up in Scribus, and the other half upside-down. Do both halves in your display's native upright direction, and then flip the one half before printing. Rotate using the dialog box under Item -> Transform...
I don't know of a way to enable non-destructive rotation in Scribus, sorry. If you're feeling adventurous, you can try out the 1.5.x release candidates ( https://www.scribus.net/downloads/unstable-branch/ ), but the release candidate installation seemed to ruin the config file for my 1.4.x install, so I'm waiting for a stable 1.6.x release.