For those wondering [email protected] is [email protected], you basically help scientists simulate extremely complex interactions with proteins and stuff by installing a program. When your computer is not in use it'll be tasked with performing calculations for the project.
With the same technology you can all help find the highest cactus in Minecraft by using your PC's processing power
Alternatively you can use this to help find a cure for cancer or whatever
For me, the biggest upside out of banano is since it doesn't require mining, you can still "mine" banano with your home computer while participating in medical research through [link]. The project is called [link] and rewards banano. For example you can currently give your computer power for research against COVID.
remember last year when [email protected] became the first exascale supercomputer through millions of people donating their computers processing time and now there is a potential shelf-stable COVID cure on the horizon as a direct result of both that and the open-source, nonprofit nature of the endeavor? Imagine what these could do for humanity
Thanks! It’s super easy to set up. You can also choose which disease you want to help with. There’s a lot of Alzheimer’s work with folded proteins... they are starting up Ebola research right now as well to look for cures...
here’s the scientific papers they have already published:
Some drugs are already in clinical trials directly due to folding at home.
Also, thanks for the condolences. My mom was 60 years old, ran her and my dads small architecture firm, self taught accounting, taxes, excel, quicken. Never smoked, 1 glass of wine a day... She grew up on a farm with her 8 brothers and sisters, she and her sister had to live in the root cellar of the house since the farmhouse was full... they were on the border of Montana and Canada so it was cold as hell. She shoveled all the snow, did all the yard work, gave to lots of charities... I miss her every day.
"AMD cards can often get default performance on much lower voltages, but you have to run tests for an hour to confirm stability. I lowered power usage of my 2990WX by 100w with only a 5-10% performance loss, depending on the program. I use this computer to fold 24/7, and the savings really add up over the year."
The replies are funny but if you really didn't understand, here you go
[email protected] has a blog post that says no here. "TL;DR: DeepMind’s AlphaFold marks a tremendous advance in our ability to predict the dominant structure of a protein. How proteins get there, and many other problems related to protein folding, remain unsolved. Synergies between AlphaFold and [email protected] could enable more progress."
[email protected] is simulating this protein as I'm typing this. Everyone can help by donating their unused CPU/GPU power. More information about the project here.
It’s called .
You need a wallet, like Kalium, then register it here:
When setting up the FAH Client, you enter in the User ID and Team ID from the bananominer website!
I’ve thought about this problem for a long time. That to not just use the vehicles for autonomous driving but to be able to use the compute to help build the models and whatever else you want.
The think of it like Folding at Home or SETI @ Home where Tesla now has the ability to task that compute capability.
So perhaps Tesla could introduce an option where you allow Tesla to use your compute when you aren’t driving and are charging for other purposes and receive some benefit for it.
It’s not hard to realise that for most cars they spent hours per day plugged in doing nothing where as that compute could be put to better use.
It gives you what your computer can handle. You actually download the packets then your computer crunches them. They can be big or small packets, depending. https://foldingathome.org/ is the site. Read it over. If you want to set your computer to doing it at night, do it. Thats what I have been doing with an old laptop, just folding 24/7. Had it working on COVID for a good long while.
There is also software like SETI that you can run in the background on your PC called . It's basically going through the almost infinite variations of protein folds and helps researchers crunch data.
Well, it looks like the have directed the efforts to look at how COVID-19 interacts with human proteins.
Folding at Home has been around for over a decade. They've been cited in research papers before. This is very legit, and does help further scientific research.
[email protected] - using your gpu for folding sequences to help understand various disease and viruses and such
[email protected] - Using your gpu to help find extraterrestrial life
Eyewire - A game that helps mapping neurons
It's fairly easy to get started.
1. Get the right [email protected] client for your system
2. Add the proper info for your DOGE wallet / DOGEfah team number
3. Set client to Medium or Full load to make sure your system kicks in if you're set to run on Idle
4. Wait for luck. There are only so many payouts that can happen every week as they can only pay out 1 DOGE at a time and there are thousands of folders and only a few dozen coins to pay out and it largely only happens for those at the top.
Put your wallet address into [link] and it will give you a user ID and a team ID, you input those into [email protected] and start folding. After 24-36 hours you will get your first payment into your wallet. Thats about it. Its super easy to set up.
This page should tell you everything you need to know about a passkey [link]
You could show them these pages:
Also, when you are folding, the Web Control page shows what project you are currently contributing to and who manages it. In my case:
"This project simulations the dynamics of the human enzyme lactate dehydrogenase (LDH), the key metabolic enzyme that converts lactate to pyruvate and back. We are simulating apo and holo-state dynamics to study how this enzyme binds inhibitors, which should lead to a better understanding of allostery and inform new computational drug discovery efforts.
This project is managed by at Temple University.
Dr. Voelz's research focuses on using new simulation methods to unravel the mysteries of how proteins self-assemble into their functional folds, and to design folding and binding properties of proteins and peptide mimetics from first principles. The Voelz Lab participates in the [email protected] project, hosting two servers at Temple University. Dr. Voelz was formerly a postdoctoral scholar in the Vijay Pande lab at Stanford University."
> [email protected] (FAH or [email protected]) is a distributed computing project for simulating protein dynamics, including the process of protein folding and the movements of proteins implicated in a variety of diseases.
From Folding website:
TL;DR: We’re simulating the dynamics of COVID-19 proteins to hunt for new therapeutic opportunities.
The TeamBiscuit [email protected] team could use some love: [link] . There's only 39 active CPUs on the team right now.
[email protected] is a project of Stanford University for medical research. You download a program onto your PC (there's even a version that runs in Chrome if you can't run a download), it does calculations and then forwards the results to researchers. This allows doctors to do super-computer-level simulations of potential medicines without having to buy a super-computer.
So far, there have been 160 research papers that have used [email protected] data as part of their research.
You can even specify that you want your CPU/GPU cycles to go towards cancer in the Advanced settings. If you ever wanted to tell your video card to join the fight against cancer, [link] is the place to start. Once you get that running, you can enter in team number 229610 to join TeamBiscuit.
In the human body, strings of amino acids become a protein molecule by a process called folding. Sometimes those folds mess up, and when they do up they can cause serious problems such as Alzheimer’s disease and Huntington’s disease
Stanford tries to figure out the how's and why's of how proteins misfold by running thousands of computer simulations of folding proteins globally. What you are doing is running a computer simulations of a folding protein, and then uploading them back to Stanford when they're finished. These simulations help scientists better understand how a protein folds and misfolds, and therefore increasing the likeliness of finding a cure.
A more in-depth explanation can be found here: https://foldingathome.org/diseases/
Does this not count?
There's also this long review of everything [email protected] did over the past year
It's not a simple multiplier. Per this page it is weighted to fodlers who "rapidly and reliably" return work units, so your bonus will vary with your hardware, client configuration and COMMITMENT TO IMPROVING THE PLANET.
Good times when people used their idle computing power and energy consumption to projects like [email protected]. Now most people will use it for the most profitable coin, even if it produces nothing useful for humanity.
If I recall, [email protected] put out some data in the form of a game and were able to more rapidly, accurately, and cheaply map out a genome than using supercomputer time.
Maybe we're all just part of a simulation to prove out the most efficient driving patterns in a city.
Well, I don't know if it'll work, but here's what I did.
1) Install Folding at Home. Make sure it works. Probably fiddle with the light-medium-full slider until you get a combination that keeps your computer from melting down. I run mine at full because fuck it, it's February.
2) Get a Dogecoin wallet. I messed with Multidoge for a while for a couple of days and it kept dying on me and losing my wallets, so I gave up and got a paper wallet from walletgenerator.net. I've never tested this with dogecoin before, but I've used a paper wallet from here with bitcoin before a couple years ago when I thought about yoloing up a mining rig (I got nothing out of it). Follow the directions on their page. It all makes sense and is pretty self-explanatory, just DON'T LOSE THE KEYS.
3) In the Folding at Home web control console, click "Change Identity", then set your team to 226715 and your nickname to your public address on your wallet. That's the shorter one of the two.
4) Run Folding at Home, accumulate points, wait for the deposit in a week (this is where I'm at -- as far as I can tell I've followed all the directions correctly). If all goes well, they'll deposit doge to the address you set as your nickname, in proportion to the number of points you earn for the Folding at Home team.
5) While waiting, enjoy the sauna that is now the room where your computer lives. Maybe roast some marshmallows on your CPU fan, fry a couple eggs, soak in the hot tub if you watercool, etc.
We'll see next week how well it works.
It's hard to assign a probability to the chance the simulations will lead to the development a drug. However, we have previously used simulations to successfully find druggable pockets in viral proteins like Ebola (check out https://foldingathome.org/2020/03/15/coronavirus-what-were-doing-and-how-you-can-help-in-simple-terms/). In general, we are looking for potential binding sites for drug-like molecules, especially binding sites that aren’t present in available protein structures from experimental techniques. We call these "cryptic" pockets. If we get a lot more "pictures" of the protein in different poses (from the [email protected] simulations), then we have a better chance of finding pockets on the protein to drug. We’re also simulating proteins bound to small molecules to assess how tightly they bind and if they warrant further experimental investigation. From there, pharma companies get involved to help refine the drug and bring it to market.
[email protected] has spun up projects specific to COVID-19. They use your spare computer power to simulate protein folding, to help find cures and vaccines.
Is everyone here taking advantage of [email protected] to help find treatments for COVID-19?
Good karma grows tendies.
You can do lots with extra electrical power!
1) Store it for later as electricity.
This requires batteries and associated equipment that monitors when you're over-producing, and stores the energy appropriately, and then is able to pull that energy back out and feed it into your home's grid when appropriate. Sadly while this is the 'ideal' thing conceptually, it's quite expensive often. :(
2) Store it for later as thermal storage.
You don't need heat, but what about cooling? You can use excess energy to cool down something with a high thermal capacity (say, water?) and then use that to cool something else off later (like your food, a room, or the whole house even).
Again though, this could be expensive. But it can be as simple as a chest freezer that you freeze ice packs in when you have excess power, and use them to keep your lunch cold. :P
3) Tailor your usage so you're using more when you have it, and less when you don't.
Sunny day outside? Do your laundry. Charge your power tool batteries. Charge your Electric Vehicle if you have one.
Cloudy Outside? Maybe do the laundry later. Turn some lights off.
4) Do something fun with it.
When you're overproducing, you could of course use it to do something like a CPU/GPU-power-hungry task, such as mining Crypto-currency or [email protected]. While these and others like them aren't strictly speaking very profitable to you a lot of the time, they make it so the power isn't completely wasted. And maybe you get some entertainment out of it!
That depends on what you consider significant. I don't know of any major EUREKA moments that have filled in major gaps in our understanding, but there have been hundreds of papers written describing the relationships they see. As far as I know a lot of the work is just preliminary findings which then have to be double checked using other methods to verify.
Personally I am a huge space and astronomy nerd. I run [email protected] (simulates various properties of the universe), [email protected] (measuring black hole spin and looking for quasars), and PrimeGrid (searches for new prime numbers.) I mainly run PrimeGrid because it earns lots of GridCoin, and the other two are because I want to support the science they are doing.
The [email protected] site always has news about their latest updates etc. https://foldingathome.org/news/
There are some good suggestions on utilising the ram so I would comment on the CPU. In a system with 32 GB ram where you hardly use 4 GB, I would assume you have lots of cpu idle time so I would suggest to donate some processing power for folding at home
I use my graphics card to Fold at Home, helping with medical research. Optionally you can join team banano and get rewarded with a potassium filled cryptocurrency which doesn't take itself too seriously.
[email protected] allows duplicate usernames, so I guess it's useful to them as a way to secure your account to an email. They have a FAQ here: [link]
I don't exactly get it but I also don't mind tossing [email protected] my email since they're an old, well regarded, and independent project that doesn't sell data.
Turn it on, download the [email protected] client from foldingathome.org, make a wallet on vault.banano.cc, and follow the instructions on bananominer.com!
You use your cpu and gpu to help "fold a protein" which in turns help scientists to complete their research faster.
It allows the researchers access to more processing power by sending individual tasks to different computers around the world.
You also earn DogeCoin each week based on your portion of the work.
For more info check out the website.
> First, I think Bitcoin fans could make a better argument regarding efficiency if they were able to demonstrate that the renewable energy they use to mine did in fact go to waste. If not, why not? If these are new power plants why would governments build unneeded power plants?
As I said in my original response, "Hey it's better than wasting energy on nothing" has to be one of the lamest justifications ever.
Anybody who is generating energy, who is wasting energy, that's a serious design flaw in their entire business model and energy generation design. To use that for crypto would be doubling down on poor planning and design.
It's business 101 to not waste resources.
In fact, this illustrates a serious flaw in bitcoin's design. Why just have those miners guess random numbers? Why not have them participating in a productive pursuit like folding at home where collective, distributed computing power could actually benefit mankind? It wouldn't be that difficult to figure out a way to create a blockchain in the process of performing socially important computations.
But that idea is completely alien to a bunch of greedy narcissists.
Seriously, if Folding At Home figured out a way to create tokens through their work, even I would be on board with that. At least all that energy would be doing something positive for mankind.
Folding at Home allows you to use extra computing power to assist them with complicated medical data.
Right now they have a special effort to use that computing power to manage data surrounding the worldwide COVID pandemic.
AFAIK your only choice for a medical project at the moment would be [email protected]. It is not a Boinc project but if you set Folding to run only on GPU and Boinc only on CPU they will coexist with no problems.
Also, I'd suggest you to try not to limit the CPU usage in Boinc unless you have problems with overheating. Boinc projects run at a lower priority, so even if you set 100% cpu usage you should not have performance issue. Or at least, you can give it a try ;)
If you want to remain on the Boinc platform also for the GPU there are some projects that will work with Ati GPU but not medicals. I have in mind Einstein, Milkyway, Primegrid, Numberfields (perhaps)... I am sure there are others. IMHO don't do neither Collatz nor Moo Wrapper because they seems rather useless.
The best thing you can do is stay at home. With that being said, check out [link] if you want to donate your computer’s background CPU and GPU time to researchers and clinicians.
In short, [email protected] builds the virus's protein atom-by-atom. The finished result allows scientists to study and it find a cure or vaccine. Since this is incredibly difficult for one computer to do, [email protected] uses many computers to complete work units to contribute to an all around greater result. This is called distributed computing.
Somewhere here on reddit i read that it's not fixed (it's adapted depending on the number of people participating). Also, it's not linear, e.g. if you have a really high PPD your payout actually gets decreased in order to distribute the BAN more evenly.
Note that you'll have to finish at least 10 WU's and use a passkey (see [link]). Before that you will not be credited the full points (you'll only get around 10% or so) and your userid will also not show up in the official statistics.
As the imgur comments said the purpose isnt money why not donate the computing power to science and start folding with your heater?
Keep yourself warm and toasty with the feeling of saving lives!
…0%. The only things that really use your devices' idle computing power are malware or things you explicitly set up yourself like [email protected]. Consumer computing resources are far too unreliable to be used at any sort of scale in real-world settings; big companies literally have entire divisions dedicated to making sure their tightly controlled systems still function as intended, and any of those DevOps/SRE/SysAdmin/IT people would run screaming if you asked them to run their infrastructure on such an unreliable platform.
Sounds like Folding at Home, which is not a game. It’s an organization that utilizes volunteered CPU/GPU power to the protein unfolding algorithms. It helps find structures in diseases, and you contribute to health science! It runs in the background on your PC and there are other ways to benefit. Here’s the website if you’d like to help! It’s pretty sweet.
We're probably well protected against ACE2-binding SARS-CoV types; they can only mutate their spikes so much and still be able to bind ACE2, such that our antibodies likely remain at least decent efficacy at identifying and destroying the virus based on spike structure. However, MERS-CoV bound to DPP4 so we're obviously not insulated from all coronaviruses currently.
There is some promising research for anti-viral therapeutics which potentially work on all coronaviruses regardless of which protein their spikes bind to. Of course, therapeutics just keep you from getting too sick, typically when taken within a timeframe from when you become symptomatic. They wouldn't stop the spread of something like SARS-CoV-2, but they could bring the hospitalization and death rates down significantly. I suppose if they had no side effects and were inexpensive, people might be able to take them as a preventative, which could help stop spread? I'm not that knowledgeable.
According to their website, folding with GPU is currently not supported on Macbook.
But here's some potassium to soften the pain.
Here is the link for Banano Miner. You then download [email protected] and use the team number and name from BananoMiner to configure your [email protected] setup
The USAF isn't the only one, the Stanford's [email protected] program make use of this technology in many health researchs.
The [email protected] COVID Moonshot effort is entering a critical phase, as it introduces weekly sprints to identify compounds that can be developed into therapeutic drugs to inhibit the main viral protease of SARS-CoV-2. Your spare GPU power is especially needed right now, as there are hundreds of thousands of work units to run through each week to continuously inform the chemists designing these drugs.
Start folding today!
If anyone wants to help fight this virus there is a program called folding at home. What it does is essentially make your computer part of this huge supercomputer with other computers to help run simulations that could end up as cures. Including COVID-19. here's the link: https://foldingathome.org/
It's complicated. On one hand we are in the middle of a pandemic and we need resources to provide relief. On the other hand the WHO is extremely corrupt and helped with cover ups, and if we want to incentivize them to correct for that then we have to use our only leverage which is money.
I would personally argue that now probably isn't the best time to do that as long as they're actually helping now (which they are; they've always done some amount of good along with the bureaucratic bad), but also that we shouldn't be going out of our way to personally fund them specifically. Instead, perhaps we should maintain their funding until this pandemic blows over and in the meantime help out with things such as vaccine development (which you can actually help with at home without donating money).
There could also be an argument made for reallocating funding that was to go to the WHO into other areas, but how we would do that is the question since I personally don't know of an alternative to the WHO that fulfills its purpose.
If you're looking for overclocking stuff, I don't do that. I just restricted the last pstates to keep temperatures down, since I am running [email protected] in the background and don't want it to be at 110°C the entire time. My information comes from the Arch wiki. I have not tried modifying voltages or frequencies of pstates yet, but that should also work. I would recommend a lot of caution if you tried it, since a wrong number might damage your card.
Hi there, currently it's not possible to circumvent because the [email protected] APIs doesn't support SSL Ceritifcates through the open source alternative.
However if you'd like you can use the desktop client as long as you put in your ID and Team ID.
Find more info here:
> I'd just like to be useful.
Blood/plasma donation. Sperm/egg donation. [email protected] if you have a computer you can contribute to science in a way that makes a difference, yet requires little effort on your part.
You sound like a genuinely decent person, world needs more like you.
I'm not a good person.
Sure, I help when it doesn't cost me too much, and I don't screw anyone over, but compared to the good I could be doing it's nothing. I could sacrifice all my disposable income to save lives, but I'm too self interested not to. I went to see a movie last week, instead of donating that money to medical science. Yeah, it's normal to do this...but it's also a little evil if you think about it enough. It's like there's someone dying of thirst next to me, and I'm over-hydrating myself, going beyond necessity and indulging in luxuries like buying a computer, netflix etc instead of literally saving lives with that money. This bothers me, but not enough to change from normal self interest to compassionate selflessness.
Your comment isn't entirely true. Not all cryptocurrencies are based off of a mining system. You're referring to Proof-of-Work (PoW) coins, which are the original style of crypto. However, many new coins now use other consensus methods, like Proof-of-Stake (PoS). This doesn't use mining, instead using a minimal amount of computing power. Instead of rewards being tied to how much work you did (aka mining), they're tied to how much of that cryptocurrency you own. There's more nuance to it, but that's the general idea.
Some popular cryptos, like Ethereum (which most NFTs are based off of) are moving from PoW to PoS right now. This should cut the power consumption by as much as 99.95%.
There are even more consensus mechanisms, like Proof-of-Useful-Work (PoUW). An example of this would be Banano, which pays you based on how much work you contribute to [email protected], a program which uses volunteer computing power to solve medical problems. Anyone who "mines" it is using their PC to help researchers find treatments for diseases like cancer, alzheimer's, and covid.
With [email protected], what did you try to get it working?
You need the username and team provided by bananominer, generated from your Banano wallet address. There are also a minimum number of work units that need to be completed before you get a payout.
If you decide to give it another try, also get a pass key for a boost from here: [link]
Go to bananominer.com first and input your address, and you will get a User ID and Team ID. You must input the User ID and Team ID into the [email protected] client in order to get rewarded.
There is more to protein folding than just the final state. Here is a good explanation by Greg Bowman(director of [email protected])
If you can spare/afford to donate the electrical usage, consider . Distributed computing app for protein folding modeling, kind of mining for science.
No requirements, I only have a CPU and can run it. The better the graphics card, the more you can fold per day but the bananos you earn don't correspond linearly to your points from folding
You might find your cpu model here: [link]
Cpu folding is not very efficient, though. And currently there is a shortage of cpu work units.
The easiest way to find out is to download the [email protected] client - it is lightweight and you can set it up in minutes: [link]
Edit: As for the amount of rewards for points ratio, it's fluctuating. Currently, you can earn about 40ish ban for around 140,000 points, I think.
[email protected] home is a client with which you fold proteins for scientific research. The program is independent from banano but the devs use it to distribute banano. [link]
I mean, maybe they are lying, or incompetent, when they discuss this point and disclose the general formula here.
>The [email protected] software on your computer calculates Total Points as follows:
final_points = base_points * max(1, sqrt( k * deadline_length / elapsed_time))
Note that the max(1, …) ensures that final_points are never lower than base_points,
[email protected] may have found the path for a therapeutic that could be effective not just against SARS-CoV-2, but all known coronaviruses. Of course, always good to pursue multiple approaches (DreamLab, etc.) in case one path doesn't pan out.
I'm mining crypto off the free electricity. They said we can't bring space heaters, but they didn't say anything about graphics cards.
If you want some extra heat, help fight COVID at the same time by doing some protein folding with your spare computing power.
The angst isn't uniform. There are a lot of incentives for faculty, especially junior faculty to take students. And not all labs have been impacted by covid equally. My lab works with pre-existing data sets and does simulation work, so our research pipeline hasn't been drastically influenced the way that wetlabs have been.
I did halt nearly all simulation work and dedicated those resources to [email protected] (for COVID research)
>Oh cool! Kind of like Uber or Lyft where the users fill all the roles and the service just organizes. Thanks for the explanation
i hate this analogy.
sheepit is exactly like folding-at-home, except instead of research, it's rendering.
Not all of the data is going to result in a landmark breakthrough. But the simulations researchers need to run take time and are expensive.
A lot of the data is for esoteric pieces of an equation that has hundreds of variables so it's not going to be "after 1,000,000,000 CPU hours we've unlocked the cure to cancer!" or anything. It will be more like, we've identified the molecule shapes most likely to bind to these sites as part of drug research, that may pan out to something with more research in a few years.
You're helping them crank through failure faster in most cases.
I run it in the winter as a "do good" spaceheater - same amount of electricity and heat as a space heater, but it does something good.
You can read about [email protected]'s research contributions here: https://foldingathome.org/papers-results/
Aca tenes algo mas de informacion al respecto
Eso es para el covid-19, pero en realidad se trabaja en un monton de otras cosas tambien, como el cancer de mama, alzheimer y otros. En la pagina hay mucha info sobre todo eso
Hey, if you want some more internet points to track then join [email protected]. Takes just a few minutes to set up. Then when you get a work unit you can watch your progress bar fill. After that you can checkout how many points you have. If you joined a team (225605 for pcmr) you can track your progress like a leader board.
All while helping scientists and doctors research covid-19. When this is over you can then focus on a particular cause like alzheimer's, cancer, huntington's, parkinson's, or just leave it on any.
All at the cost a little or a lot (set it up how you want) of your computers processing power. You can also set it up to only run when the computer is idle. If your computer was built in the last 10 years or so you'll be fine.
I think its called "folding at home", but I dont know if it's for caronavirus yet. They have don cancer and alzheimers research though. Linus tech tips has folding month once a year and have a contest so I'm fairly sure its legit.
Here is a link [link]
Our projects utilize either the CPU or the GPU so generally any modern CPU can contribute to our efforts! If you're computer is half as fast as a newer computer, you're machine would just do half the work in the same amount of time as the newer computer. Either way, it is still really helpful and you are directly contributing to good science :D
If you are feeling particularly generous, or want to have an impact in a different way, we accept donations to help us keep up with our software engineering needs and maintain all the hardware that sends/collects the data you help us generate (https://foldingathome.org/about/donate/)
Here is the link to the original article, and even NVIDIA has asked on their Twitter for fellow gamers to help with the computing load.
If you also want to contribute simple go to Foldingathome.org and download the client to put your computer to work!
By visiting this link and downloading Folding at Home:
It is programm developed by Stanford University, that uses your computers processing power to simulate different medications and their interactions with the virus.
My pc has been folding all day :)
I don't think that's available (yet?). See this:
>Given this information, we are uniquely positioned to help model the structure of the 2019-nCoV spike protein and identify sites that can be targeted by a therapeutic antibody. We can build computational models that accomplish this goal, but it takes a lot of computing power.
>This is where you come in! With many computers working towards the same goal, we aim to help develop a therapeutic remedy as quickly as possible. By downloading [email protected] here [LINK] and selecting to contribute to “Any Disease”, you can help provide us with the computational power required to tackle this problem.
Blue Thunder is out of touch with current events related to folding. It is no longer being run out of Stanford, and one of Dr Pande's former associates is the current director. See this announcement and others from their News page - [link]. The move off Stanford servers was last year.
Definitely worth it to go prebuilt.
Also, as an aside you or he might be interested to know that just because he wants to game on it doesn't mean the PC can't be put to other good uses when he's not using it. Check out foldingathome.org
I can help you with your second question:
> Folding refers to the way human protein folds in the cells that make up your body. We rely on the proteins to keep us healthy and they assemble themselves by folding. But when they misfold, there can be serious consequences to a person’s health.
On a similar note, if anyone of you wants to donate computing power for disease research, or cancer exclusively if you select that, you can use the program “[email protected]”[link] also be careful, setting it to max and to use all threads will send you PC to throttle town, you can configure how many threads it uses in the advanced controller, instead of the web controller
I think the things they're referring to as immediately accessible is specifically the likes of [email protected], where you wouldn't do anything -- your computer does it all automatically!
For the cleaning up data sets thing... it won't be CS related at all. It's 110% not as glamorous or fun as you expect. I believe they're referring to the likes of mturk, where people work for pocket change by doing menial tasks of any kind. Some tasks on those sites involves things like categorizing the data of data sets so that it can be used for machine learning (the algorithms need to know if they guessed correctly, as well as training data requires knowing the category immediately). I've never used mturk and can't say how easy it would be to focus on a specific type of work or how much work is available. But I can say it's pretty much as unrelated as it gets to the kind of work you'd actually do with a CS degree.
https://foldingathome.org/?lng=en-US its a distributed system where users can donate their cpu and gpu power to solve complex problems, with the goal of helping find cures or answers to different diseases. So I want to get a computer that I can have do this 24/7
You have a ton of eye opening information here, thank you for the complete rant. My only argument would be the claim that the vaccine was rushed. Usually a vaccine, like the annual influenza vaccine, is made by the same groups of epidemiologists, folding proteins, and using data models to predict how the next strain will mutate.
The longest part of this process is folding proteins. And this is how we get the impression that a vaccine takes <this.long>. For a worldwide pandemic, there are more teams is epidemiologists working together, and there are more computers helping fold proteins.
[email protected] is an app that allows all of us to donate processing power from our own computers to folding proteins. I've been donating processing power from my gaming PC for nearly two years. Work that took weeks or even months is completed in hours. This is why there is the false impression that the vaccine was rushed. Instead of one group of epidemiologists working linearly, many groups of epidemiologists were working concurrently, and they didn't have to wait for results from folding.
I feel like nobody will see this in all of the replies but I'll put it out there anyways. There are distributed computing projects that run models on a variety of diseases and conditions in an attempt to find ways to combat them. Folding at Home is a good one; it only uses the system resources on your computer that you are not using and do not need, and it uploads the data from it's computations to the project. Check it out so you can help find a treatment/cure/prevention for a lot of things:
Well instead of solving some random hashes, you could have a miner network which uses CPU/GPU power to solve some real world problem such as the [email protected] project to help scientists simulate proteins interaction and even develop Covid-19 vaccines, miners can be paid in crypto for their effort similar to mining for BTC.
To be honest, I'm new to it as well and I've only used the command line client on unix, but it looks like there's some instructions here for the GUI client. You were on the right track with the Expert tab in Configuration. Under Extra client options, it looks like you can add an entry for max-packet-size and set the value to small.
In my experience, changing options/flags like this won't take effect until the next work unit, and you may need to quit and restart [email protected] as well.
Folding at home.
A link to the archive of the old Stuffcoins website, before the owner ran away with the doge
Quem quiser botar seu computador pra uma boa causa ajudando a ciência e como recompensa ganhar um pouquinho de cripto, existe o projeto [email protected]!
No [email protected] você coloca o seu poder computacional à disposição da ciência no estudo de enovelamento de proteínas, que é algo que nos ajuda a entender melhor uma variedade de doenças como câncer, alzheimer, parkinson, doenças infecciosas e até o Covid-19!
Como recompensa por esse auxílio você recebe Banano. É uma recompensa simbólica já que Banano não vale quase nada e não possui um projeto com grandes ambições, mas o foco principal aqui é realmente ajudar a ciência!
Add a passkey, it's very easy to setup and will increase your BAN reward by a large margin.
Skl my favorite meme coin so far, Banano. Fork siya ng nano so it's feeless and instant din. You can "mine" the coin by using https://foldingathome.org/. Basically, the coin is free through faucets and the community is really chill and fun
Bananominer works differently from other cryptos, its not actually crypto mining, instead you "mine" banano by completing work units for folding at home, which is an organization that uses computer processing to contribute to medical research. The more points you get for folding at home, the more banano you earn. Its a really simple process to setup, simply go to the [email protected] site and download the client, and then you follow the instructions in this video to get it setup with banano. If your graphics card doesn't show up in the [email protected] client, follow this guide to fix it. Once it's all setup it usually takes about 24-36 hours before you'll get your first payment but after that you'll get banano twice per day. Hope this helps! :)
Get [email protected] [link] download and install, then go to [link] and enter your banano address then they will give you a group ID and your individual ID.
Launch [email protected], and input your group ID and individual ID then run the program.
Download and install [email protected] ([link])
Go to [link] and enter your banano address, Hit "Start Now" to get your User ID (Username)
Enter your User ID (Name) and Team ID into the [email protected] client (And start mining)
It's also recommended that you set up a passkey, because you'll get more points/banano if you do.
Note that it might take 24-36hrs after completing your first 2 work units (WUs) before you see any banano deposited into your wallet.
Antivirals function similarly to antibiotics: concentration of drug in blood inhibits growth. They do not need to be specific, but since they focus on a specific mechanism, some meds only work on certain things.
Since you used “antigen”, I’m going to assume you’re talking about the H and N proteins changing on the influenza virus. You don’t need to worry about that because the antiviral works via allosteric competition or whatever that inhibits the activity; it’s a global AOE effect. For antibody therapy, it would need to be antigen specific. Remember the requests for recently recovered and symptom free covid patient’s blood/plasma for ill patients? That was basically antibody therapy. The donor’s antibodies would target the antigens (virus) and clump them all together to give your body a chance to get rid of it.
The genome being stable or not isn’t the issue. We need to know the proteins it interacts with and uses. We’re doing this by digitally translating the viral genes and checking interactions to search for effective drugs. You can help by donating your computing power here: [link]
Yeah, not the way a 'gym bro' thinks of protein. Proteins are complex molecules produced as a result of gene expression, used to do many, many things to support cell function. You could think of proteins as like the hands of DNA (if DNA was a person metaphorically speaking).
The molecular structure of proteins can be incredibly complicated as, among other things, they 'fold' in on them selves many times. To understand a molecule/proteins function you must know its structure. Computers can figure out a new proteins structure with the right software, but it is incredibly CPU intensive. Thats were the [email protected] project, and by extension theta come in. They use your computer to partially solve the complex structure of a target protein.
This is the [email protected] link: [link]
They are actually using CPU to screen Covid treatments (treatments based on protein application I assume). Crazy.
Theta is not only Godzilla, but the cure for COVID haha
I should also mention that the cryptic pocket [email protected] found may be effective against all coronaviruses. If that's the case, barring major mutation, we might never face a coronavirus epidemic or pandemic again.
If you haven't set a passkey up. I had that mistake months ago. You should get 800k PD. I have GTX 1660TI mobile that gets around 950k PD
No idea if any projects from this helped develop any of these vaccines, but if you have spare computers laying around, or using your main PC, please consider running [email protected] to help researchers. They've always done cancer/other diseases, but they have an entire COVID selection now. It will make your energy bill go up and turn your PC into a heater, but it's worth it.
If you only have a laptop, I wouldn't recommend it, since it will heat it up quite a bit.
My brain is checked out for the night, here's this quick read. Also, many research groups are only funded by grants. Speaking from personal experience, grants take a lot of time.
Edit: good question though, had to look it up.
The servers are housed at Stanford University. You can read their statements on data and privacy. It does collect some information about your system to intelligently assign work units.
Thirty years ago would be 1990. Some people had the ability to send emails over the Internet but it was very rare. Compuserve was a big online gathering point. Usenet newsgroups and listservs would have been the primary avenues of discussion online. Without the electronic dumpster fires of Twitter, Facebook, YouTube, etc. there would have been less misinformation spread in an electronic fashion. News about the virus would have flowed from the TV networks out to viewers. We probably would have fared better. Now, everyone with a decent PC and a broadband connection can share their mental diarrhea with the world.
I guess the biggest downside to battling a pandemic in 1990 would have been the absence of [email protected] as well as the supercomputers the US has contributed to the fight against the coronavirus.
After we have defeated (or at least survived) the coronavirus that causes covid-19, I think our success will be attributed to the vast array of information sharing tools and computing resources available to researchers in the year 2020. The battle is no longer each country alone against the virus but researchers around the world working together in ways never seen before to defeat this shared enemy. Among the weapons those researchers bring to bear against the virus is the most powerful supercomputer ever constructed by humankind.